Reaxys is a fully integrated content source providing in-depth coverage of inorganic, organic and organometallic small molecule chemistries excerpted from appropriate journal and patent literature.

Reaxys is a fully integrated content source providing in-depth coverage of inorganic, organic and organometallic small molecule chemistries excerpted from appropriate journal and patent literature.

Reaxys was created through the merger of the existing CrossFire databases into a single database with a new and intuitive user interface. These databases have been harmonized and merged into a single database with standardized and harmonized data fields (same field names, units, and formats).

At the heart of this Reaxys philosophy is the concept of "chemistry as the organizing principle". This means that the chemical compound or reaction is central to the way in which the data is organized in the database. This is fundamentally different from bibliographic databases in which a journal or patent record is at the center. This chemically focused approach allows all data from multiple sources to be combined together in one de-duplicated record for a given compound or reaction (i.e., a single compound or reaction can have multiple source citations whereas a bibliographic database will have one record per published item, so the same compound or reaction may be found in multiple records).

Reaxys contains an extensive repository of experimentally validated data including structures, reactions (including multi-step reactions), and physical properties that are invaluable to chemists in their daily work. The underlying scientific model is based on reliability, relevancy and scientific objectivity and echoes the traditions of the great 19th century handbooks: Handbook of Organic Chemistry and Handbook of Chemistry, published by Friedrich Beilstein and Leopold Gmelin.

There are three core principles guiding the excerption and creation of the database. Small molecules (organic, organometallic and inorganic compounds) are only excerpted if they have:

1) a chemical structure

2) an experimental fact (property, preparation, reaction)

3) a credible citation.

The consequence of applying these core principles is a consistent, reliable, factual database.

Functionalities and Capabilities

In addition to the standard features inherited from the CrossFire interface, new search, analysis, and workflow tools have been designed and developed to assist with the most frequent and common tasks:

• Synthesis planner to design optimum synthesis routes

• Multi-step reactions to identify precursor reactions which are required for the synthesis of target compounds

• Additional search capabilities such as the ability to generate a structure query from names or phrases

• Search result filters by key properties, synthesis yield, or other ranking criteria

• Intuitive results visualization

• Chemical sourcing and procurement options from eMolecules

• Chemical safety information from Hazmat Navigator (an online workflow solution which provides chemical safety information including toxicity, reactivity and the safest way to handle chemicals)

• Real time citation information from SciVerse Scopus (the largest abstract and citation database of peer-reviewed literature and quality web sources)

Reaxys' chemistry literature sources

The aim is to select the best and most relevant coverage, of the highest value to the chemist, from the most important and chemistry- rich literature and patent sources. These selection criteria are revised on at least an annual basis.

Working closely with key customers, Elsevier has identified some 2000 journals associated with chemistry, by analyzing the citation patterns of the papers that provide the highest density of chemical information. These range from true chemistry journals (such as J. Am. Chem. Soc.) to journals such as The Lancet, which occasionally cite chemistry journals. The journals most relevant and important to the needs of the research chemist have been identified from this journal space; this list is continuously refined and augmented. From this list relevant, individual papers are then identified, and all appropriate data excerpted.

To add some perspective, in 2010, the top 20 journals from which the largest amount of data was excerpted for Reaxys are as follows:

Advanced Synthesis and Catalysis

Angewandte Chemie International Edition

Bioorganic & Medicinal Chemistry

Bioorganic & Medicinal Chemistry Letters

Chemical Communications

Chemistry - A European Journal

European Journal of Organic Chemistry

Journal of the American Chemical Society

Journal of Medicinal Chemistry

Journal of Organic Chemistry

Journal of Organometallic Chemistry

Organic and Biomolecular Chemistry

Organic Letters

Organometallic Chemistry



Synthetic Communications


Tetrahedron Asymmetry

Tetrahedron Letters

For patents, the selection is based upon the International Patent Classes [IPC]:

C07 Organic Chemistry

• A61K Drugs

• C09B Dyes

English language patent publications from the above IPC classes are excerpted from the following Patent Offices: PCT (WIPO, 1978 -), European (EPO; 1978 -), United States (USPTO; 1976 -). (The date in brackets indicates when coverage started.)

More news

Nature Publishing Group (NPG) publishes a portfolio of journals including Nature (founded in 1869) the leading weekly, international scientific journal. It is ranked the world's most cited interdisciplinary science journal according to the 2010 Journal Citation Reports Science Edition (Thomson Reuters, 2011). Its Impact Factor is 36.101.

ESI users can determine the influential individuals, institutions, papers, publications, and countries in their field of study – as well as emerging research areas that could impact their work. ESI database can be accessed within the framework of TÁMOP 4.2.5 application won by Educatio Public Services Non-profit LLC, by institutes applying for it.

EconLit (Economic Literature Index), published by the American Economic Association, is the world’s biggest database in the fields of economics and related subjects. It provides bibliographic coverage of a wide range economics-related literature, going back to 1969, and covers both economic theory and application.

Arcanum Magyarország vezető tartalomszolgáltatója
Digitális Tankönyvtár felsőoktatási tankönyvek egyetemi jegyzetek folyóiratcikkek elektronikusan